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Welcome to the inaugural edition of our Cure in Progress Report! As the Executive Director of CureGRIN Foundation, I’m thrilled to launch this new way of connecting with you. My goal with this report is to provide you with transparent, hopeful, and regular updates on the progress being made towards treatments and cures for GRI Disorders.

Researchers at the University of Toronto tested whether repairing a Grin1 mutation in mice can restore cognitive function. In the article, “Consequences of NMDA receptor deficiency can be rescued in the adult brain”, they report that adult mice born without functioning NMDA receptors (NMDARs) recovered cognitive ability with gene editing.