GRID Disorder is part of a larger family of genetic diseases related to ionotropic glutamate receptors and is caused by a change in one of four GRID genes including GRID1 and GRID2. These genes contain the code to create the δ (delta) receptors. There is not a lot known about these receptors, but we do know that they play important roles in neuronal development.  

We do not have a clear sense of how common GRID Disorder is yet because so few patients have been reported in the registry and scientific literature. 

To date, there have been no potential treatments identified targeting the delta receptors for GRID Disorder. 

CureGRIN plans to work with researchers, clinicians, biotechnology companies, and pharmaceutical companies to encourage and help facilitate the development and testing of treatments for GRID Disorder patients.