About Us
CureGRIN - Our Mission
CureGRIN Foundation is dedicated to improving the lives of people around the world with GRI Disorders (GRIA, GRID, GRIK, and GRIN) and their families through research, education, and support. We work closely with scientists and the medical community to drive patient-centered research that will lead to treatments and cures.
GRI Disorders may be rare, but hope should not be.
Our Roots
CureGRIN was initially founded by parents of children with GRIN1, GRIN2A, GRIN2B, and GRIN2D variants. CureGRIN had been established for a few years prior to being contacted by a GRIA family who asked if we would consider also including the GRIA and GRIK genes. After learning more from clinicians and researchers about how similar the disorders are, we expanded our mandate to include all ionotropic glutamate receptor genes.
This includes: GRIA (GRIA1, GRIA2, GRIA3, GRIA4) genes that encode the AMPA receptor, GRID (GRID1, GRID2) genes that encode the delta receptor, GRIK (GRIK1, GRIK2, GRIK3, GRIK4, GRIK5) genes that encode the kainate receptor, and GRIN (GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D, GRIN3A, GRIN3B) genes that encode the NMDA receptor.
Parents of children with GRI Disorders leading CureGRIN. Learn more about the people behind our mission.
CureGRIN drives progress for families with GRI Disorders by funding research, hosting conferences, and empowering ambassadors to raise awareness and connect communities.
CureGRIN Ambassadors are dedicated volunteers who support the CureGRIN mission by building local connections and raising awareness for individuals and families affected by GRI Disorders.
CureGRIN’s Advisory Boards are made up of leading experts, clinicians, and advocates who guide the foundation’s mission. Learn how their expertise supports CureGRIN’s efforts in research, advocacy, and our long-term strategy.
CureGRIN’s valued partners and leading organizations, collaborate to drive progress in research, advocacy, and resources for families affected by GRI Disorders. They help strengthen connections across the broader rare disease community.
Have questions, ideas, or want to get involved? Whether you’re a family seeking resources, a researcher, or a potential partner, we’re here to listen and help.
Our Goals
Our goal is simple and bold: To find cures and therapies for people around the world suffering from GRI Disorders.
CureGRIN is committed to ensuring collaboration between clinicians, researchers, biotech companies and patient advocates, sharing everything from theories and results, to animal models and technologies.
We follow a three-pronged approach in our effort to find a cure for GRI Disorders
- Drive the research agenda to find treatments and cures by the end of the decade.
- Unite and empower the global GRI Community.
- Strengthen operations, governance, and revenue in order to achieve our mission.
We have developed a Research Roadmap to address the 10 Essential Questions that need to be answered in order to find treatments and cures. CureGRIN will be investing $900,000 to answer these 10 Essential Questions in 2022, but this is only the beginning!
We are driving the research agenda by:
- Investing in research through CureGRIN-funded proposals, regional CureGRIN-affiliated charities, and by helping researchers secure funding from external sources.
- Deepening engagement with scientists, clinicians, and industry professionals from around the world.
- Monitoring progress on the plan through a publicly available dashboard.
Our Values
Integrity
We adhere to the highest standards of transparency and fiscal responsibility.
Collaboration
We work closely with researchers, other GRI foundations and family groups. We promote collaboration and openness between researchers.
Optimism
We believe that therapies and cures are coming that will make a significant difference in the lives of people with GRI Disorders.
ICD-10 Code
Effective 10/1/25 – the new ICD-10 code for GRI Disorders is QA0.011
